Chronic Insomnia and the Stress System

被引：209

作者：

Basta, Maria ^{[1
]}

Chrousos, George P. ^{[2
,3
]}

Vela-Bueno, Antonio ^{[4
]}

Vgontzas, Alexandros N. ^{[1
]}

机构：

[1] Penn State Coll Med, Sleep Res & Treatment Ctr, Dept Psychiat H073, 500 Univ Dr, Hershey, PA 17033 USA

[2] Univ Athens, Aghia Sophia Childrens Hosp, Athens Univ Med Sch, Dept Pediat, Athens 11527, Greece

[3] Univ Athens, Aghia Sophia Childrens Hosp, Athens Univ Med Sch, Unit Endocrinol Metab & Diabet, Athens 11527, Greece

[4] Univ Autonoma Madrid, Dept Psychiat, Human Sleep & Appl Chronobiol Lab, Madrid, Spain

来源：

SLEEP MEDICINE CLINICS | 2007年 / 2卷 / 02期

关键词：

D O I：

10.1016/j.jsmc.2007.04.002

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In insomnia, which is a very common sleep disorder, objective sleep measures, EEG activity, physiologic findings, HPA axis activity, and inflammation markers suggest that it is not a state of sleep loss, but a disorder of hyperarousal present both during the night and the daytime. Several psychological and physiological factors contribute to the onset and perpetuation of insomnia, such as anxious-ruminative personality traits, stressful events, age-related sleep homeostasis weakening mechanisms, menopause, and biologic-genetic diathesis of CNS hyperarousal. The therapeutic approach in insomnia should be multidimensional, reducing the overall emotional and physiologic hyperarousal and its underlying factors present throughout the 24-hour sleep/wake period.

引用

页码：279 / 291

页数：13

共 76 条

[1] PHYSIOLOGICAL AND PSYCHOLOGICAL DIFFERENCES BETWEEN GOOD AND POOR SLEEPERS [J].