OPTIONAL ORTHO-HYDROXYMETHYLATION OR ALPHA-HYDROXYMETHYLATION OF ALKYLARENES

被引：5

作者：

GUGGISBERG, Y ^{[1
]}

FAIGL, F ^{[1
]}

SCHLOSSER, M ^{[1
]}

机构：

[1] UNIV LAUSANNE,INST CHIM ORGAN,RUE BARRE 2,CH-1005 LAUSANNE,SWITZERLAND

来源：

JOURNAL OF ORGANOMETALLIC CHEMISTRY | 1991年 / 415卷 / 01期

关键词：

D O I：

10.1016/0022-328X(91)83276-A

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

Treatment of arenes carrying methyl or primary alkyl groups in tetrahydrofuran solution with potassium tert-butoxide activated butyllithium followed by reaction with formaldehyde gives 2-arylalkanols. In contrast, if prior to the addition of the electrophile a stoichiometric amount of magnesium dibromide is added then the regioisomeric 2-alkylbenzyl alcohols are formed.

引用

页码：1 / 6

页数：6

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