CYTOSAMINOMYCINS, NEW ANTICOCCIDIAL AGENTS PRODUCED BY STREPTOMYCES SP KO-8119 .2. STRUCTURE ELUCIDATION OF CYTOSAMINOMYCIN-A, CYTOSAMINOMYCIN-B, CYTOSAMINOMYCIN-C AND CYTOSAMINOMYCIN-D

被引：25

作者：

SHIOMI, K ^{[1
]}

HANEDA, K ^{[1
]}

TOMODA, H ^{[1
]}

IWAI, Y ^{[1
]}

OMURA, S ^{[1
]}

机构：

[1] KITASATO INST,BIOL FUNCT RES CTR,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1994年 / 47卷 / 07期

关键词：

D O I：

10.7164/antibiotics.47.782

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Structures of novel anticoccidial antibiotics, cytosaminomycins A, B, C and D, were elucidated by NMR studies. Cytosaminomycins were shown to be nucleoside antibiotics related to oxyplicacetin. Their carboxylic acid moieties bonded to the cytosine residue were different from that of oxyplicacetin. The carboxylic acids contained in cytosaminomycins A, B, C and D were (E)-3-(methylthio)acrylic acid, 4-methylaminobenzoic acid, 3-methylcrotonic acid, and tiglic acid, respectively.

引用

页码：782 / 786

页数：5

共 5 条

[1] CYTOSAMINOMYCINS, NEW ANTICOCCIDIAL AGENTS PRODUCED BY STREPTOMYCES SP KO-8119 .1. TAXONOMY, PRODUCTION, ISOLATION AND PHYSICOCHEMICAL AND BIOLOGICAL PROPERTIES [J].

HANEDA, K ;

SHINOSE, M ;

SEINO, A ;

TABATA, N ;

TOMODA, H ;

IWAI, Y ;

OMURA, S .

JOURNAL OF ANTIBIOTICS, 1994, 47 (07) :774-781

[2] A TWO-DIMENSIONAL NMR-STUDY OF ANGELIC AND TIGLIC ACID [J].

JOSEPHNATHAN, P ;

WESENER, JR ;

GUNTHER, H .

ORGANIC MAGNETIC RESONANCE, 1984, 22 (03) :190-191

[3] OXAMICETIN, A NEW ANTIBIOTIC OF BACTERIAL ORIGIN .2. STRUCTURE OF OXAMICETIN [J].

KONISHI, M ;

NARUISHI, M ;

TSUNO, T ;

TSUKIURA, H ;

KAWAGUCHI, H .

JOURNAL OF ANTIBIOTICS, 1973, 26 (12) :757-764

[4] STRUCTURE OF AMICETIN [J].

STEVENS, CL ;

HASKELL, TH ;

NAGARAJAN, K .

JOURNAL OF ORGANIC CHEMISTRY, 1962, 27 (09) :2991-&

[5]

YONGLE C, 1985, KANGSHENGSU, V10, P285

← 1 →