EVALUATION OF A COMMERCIAL RADIOIMMUNOASSAY KIT FOR THE DETECTION OF LYSERGIDE (LSD) IN SERUM, WHOLE-BLOOD, URINE AND STOMACH CONTENTS

被引：10

作者：

ALTUNKAYA, D ^{[1
]}

SMITH, RN ^{[1
]}

机构：

[1] METROPOLITAN POLICE FORENS SCI LAB,109 LAMBETH RD,LONDON SE1 7LP,ENGLAND

来源：

FORENSIC SCIENCE INTERNATIONAL | 1990年 / 47卷 / 02期

关键词：

LSD in serum; LSD radioimmunoassay; urine and stomach contents; whole blood;

D O I：

10.1016/0379-0738(90)90205-D

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

The Diagnostic Products Corporation Coat-A-Count radioimmunoassay kit for LSD in urine has been evaluated for use in forensic toxicology with a variety of sample types. The cut-offs (defined as the mean response of blank samples plus three standard deviations) for LSD in serum, haemolysed whole blood, urine and stomach contents were 0.06, 0.050-0.055, 0.18 and 0.18 ng/ml, respectively. Preliminary extraction of LSD from the samples is not usually necessary. The precision of the analysis and the recoveries from spiked samples were satisfactory. The cross-reactivities of 2-oxo-LSD, lysergic acid methyl propylamide, lysergic acid monoethylamide and nor-LSD were estimated to be 11, 6, 2 and 1% respectively relative to LSD (100%). © 1990.

引用

页码：113 / 121

页数：9

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