LETHAL PARALYTIC SHELLFISH POISONING IN GUATEMALA

被引：71

作者：

RODRIGUE, DC

ETZEL, RA

HALL, S

DEPORRAS, E

VELASQUEZ, OH

TAUXE, RV

KILBOURNE, EM

BLAKE, PA

机构：

[1] CTR DIS CONTROL,CTR ENVIRONM HLTH,ATLANTA,GA 30333

[2] US FDA,WASHINGTON,DC 20204

[3] UNIFICADO CONTROL ALIMENTOS & MED,GUATEMALA CITY,GUATEMALA

[4] GUATEMALA MINIST HLTH,GUATEMALA CITY,GUATEMALA

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1990年 / 42卷 / 03期

关键词：

D O I：

10.4269/ajtmh.1990.42.267

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

An outbreak of paralytic shellfish poisoning occurred in Champerico, on the Pacific coast of Guatemala, July-August 1987. Of 187 people affected with characteristic neurologic symptoms, 26 died. A case study implicated a species of clam, Amphichaena kindermani, harvested from local beaches as the vehicle of the neurotoxins (saxitoxins). Children <6 years old had a higher fatality rate (50%) than people >18 years of age (7%). The minimum lethal dose for 1 child was estimated to have been 140 mouse units of toxin/kg body weight; thus children may be more sensitive to the saxitoxins than are adults. This is the first large outbreak of paralytic shellfish poisoning recognized in Guatemala.

引用

页码：267 / 271

页数：5

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