INCREASED ERYTHROPOIETIN PRODUCTION IN CHILDREN WITH SEVERE MALARIAL ANEMIA

被引：56

作者：

BURCHARD, GD

RADLOFF, P

PHILIPPS, J

NKEYI, M

KNOBLOCH, J

KREMSNER, PG

机构：

[1] UNIV VIENNA,DEPT INFECT DIS,A-1090 VIENNA,AUSTRIA

[2] ALBERT SCHWEITZER HOSP,INT RES LAB,LAMBARENE,GABON

[3] INST TROP MED,D-10179 BERLIN,GERMANY

来源：

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE | 1995年 / 53卷 / 05期

关键词：

D O I：

10.4269/ajtmh.1995.53.547

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Plasma immunoreactive erythropoietin concentrations were determined in 84 children with Plasmodium falciparum malaria in Gabon. There was an inverse log/linear relationship between hemoglobin or hematocrit and plasma erythropoietin, indicating that erythropoietin levels increased exponentially as circulating hemoglobin decreased. These results show that P. falciparum malaria does not lead to decreased erythropoietin production, and in turn reduced erythropoietin production does not contribute to the pathogenesis of malarial anemia. There is an adequate response of erythropoietin to anemia in children with P. falciparum malaria.

引用

页码：547 / 551

页数：5

共 31 条

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[2]

ABDALLA S, 1980, BRIT J HAEMATOL, V46, P173

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