CORTICAL METABOLIC-ACTIVATION IN HUMANS DURING A VISUAL MEMORY TASK

被引：50

作者：

SWARTZ, BE

HALGREN, E

FUSTER, JM

SIMPKINS, F

GEE, M

MANDELKERN, M

机构：

[1] VET ADM WADSWORTH MED CTR,DIV NUCL MED,LOS ANGELES,CA 90073

[2] VET ADM WADSWORTH MED CTR,POSITRON EMISS TOMOG FACIL,LOS ANGELES,CA 90073

[3] UNIV CALIF LOS ANGELES,DEPT NEUROL,LOS ANGELES,CA 90024

[4] UNIV CALIF LOS ANGELES,DEPT PSYCHIAT,LOS ANGELES,CA 90024

[5] UNIV CALIF LOS ANGELES,BRAIN RES INST,LOS ANGELES,CA 90024

[6] INSERM,RENNES,FRANCE

[7] UNIV CALIF IRVINE,DEPT PHYS,IRVINE,CA 92717

来源：

CEREBRAL CORTEX | 1995年 / 5卷 / 03期

关键词：

D O I：

10.1093/cercor/5.3.205

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

A delayed match-to-sample (DMS) task of abstract, visual memory was performed during the uptake period of F-18-fluorodeoxyglucose. The increase in glucose uptake of cortical and subcortical regions (''activation'') during the DMS task was compared with that during a control, immediate match-to-sample task using positron emission tomography. Both discriminant analysis and paired t tests supported the observation that the dorsolateral prefrontal area underwent the greatest activation, while a factor analysis revealed the functional correlation matrices of the tasks, Activations in the ventral premotor cortex and supramarginal and angular gyri were highly correlated with the change in the dorsolateral prefrontal cortex, The basal forebrain/ventral pole region showed a smaller but independently significant change, The findings support the role of the dorsal prefrontal region in the nonspatial working memory of humans.

引用

页码：205 / 214

页数：10

共 68 条

[1]

AFIFI AA, 1990, COMPUTER AIDED MULTI

[2]

BADDELEY AD, 1990, NEUROPSYCHOLOGICAL I, P55

[3] REPRODUCIBILITY OF CEREBRAL GLUCOSE METABOLIC MEASUREMENTS IN RESTING HUMAN-SUBJECTS [J].