HIGH-DOSE INTRAVENOUS GAMMA-GLOBULIN THERAPY FOR NEONATAL IMMUNE HEMOLYTIC JAUNDICE DUE TO BLOOD-GROUP INCOMPATIBILITY

被引：40

作者：

SATO, K ^{[1
]}

HARA, T ^{[1
]}

KONDO, T ^{[1
]}

IWAO, H ^{[1
]}

HONDA, S ^{[1
]}

UEDA, K ^{[1
]}

机构：

[1] KYUSHU UNIV, FAC MED, DEPT PEDIAT, FUKUOKA 810, JAPAN

来源：

ACTA PAEDIATRICA SCANDINAVICA | 1991年 / 80卷 / 02期

关键词：

GAMMA-GLOBULIN THERAPY; NEONATAL HYPERBILIRUBINEMIA; BLOOD GROUP INCOMPATIBILITY;

D O I：

10.1111/j.1651-2227.1991.tb11828.x

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Three newborn infants who developed hyperbilirubinemia due to blood group incompatibility were treated with high-dose gammaglobulin. Hyperbilirubinemia was caused by Rhesus (Rh) incompatibility (anti-E + anti-c) in Infant 1 and ABO incompatibility (anti-B) in Infants 2 and 3. Hyperbilirubinemia was refractory to conventional phototherapy but responded well to intravenous gammaglobulin (IVGG) at a dose of 1 g/kg in all infants. No adverse effects were observed. These findings suggest that high-dose IVGG may be useful in the treatment of hyperbilirubinemia due to isoimmune haemolytic disease resistant to phototherapy.

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页码：163 / 166

页数：4

相关论文

共 15 条

[1] INTRAVENOUS TREATMENT WITH GAMMA-GLOBULIN OF AUTOIMMUNE NEUTROPENIA OF INFANCY [J].

BUSSEL, J ;

LALEZARI, P ;

FIKRIG, S .

JOURNAL OF PEDIATRICS, 1988, 112 (02) :298-301

[2]

BUSSEL JB, 1983, BLOOD, V62, P480

[3] INTRAVENOUS TREATMENT OF AUTOIMMUNE HEMOLYTIC-ANEMIA WITH VERY HIGH-DOSE GAMMA-GLOBULIN [J].

BUSSEL, JB ;

CUNNINGHAMRUNDLES, C ;

ABRAHAM, C .

VOX SANGUINIS, 1986, 51 (04) :264-269

[4]

Centers for Disease Control (CDC), 1986, MMWR Morb Mortal Wkly Rep, V35, P231

[5] HIGH-DOSE INTRAVENOUS GAMMA-GLOBULIN THERAPY FOR PASSIVE IMMUNE THROMBOCYTOPENIA IN THE NEONATE [J].

CHIRICO, G ;

DUSE, M ;

UGAZIO, AG ;

RONDINI, G .

JOURNAL OF PEDIATRICS, 1983, 103 (04) :654-655

[6] INTRAVENOUS GAMMA-GLOBULIN THERAPY FOR PROPHYLAXIS OF INFECTION IN HIGH-RISK NEONATES [J].

CHIRICO, G ;

RONDINI, G ;

PLEBANI, A ;

CHIARA, A ;

MASSA, M ;

UGAZIO, AG .

JOURNAL OF PEDIATRICS, 1987, 110 (03) :437-442

[7] HEMOLYSIS FOLLOWING INTRAVENOUS IMMUNE GLOBULIN THERAPY [J].

COEPLAN, EA ;

STROHM, PL ;

KENNEDY, MS ;

TUTSCHKA, PJ .

TRANSFUSION, 1986, 26 (05) :410-412

[8] TRANSIENT REVERSAL OF THROMBOCYTOPENIA IN IDIOPATHIC THROMBOCYTOPENIC PURPURA BY HIGH-DOSE INTRAVENOUS GAMMA-GLOBULIN [J].

FEHR, J ;

HOFMANN, V ;

KAPPELER, U .

NEW ENGLAND JOURNAL OF MEDICINE, 1982, 306 (21) :1254-1258

[9] ELIMINATION OF VIRUSES (HUMAN IMMUNODEFICIENCY, HEPATITIS-B, VESICULAR STOMATITIS AND SINDBIS VIRUSES) FROM AN INTRAVENOUS IMMUNOGLOBULIN PREPARATION [J].

HAMAMOTO, Y ;

HARADA, S ;

YAMAMOTO, N ;

UEMURA, Y ;

GOTO, T ;

SUYAMA, T .

VOX SANGUINIS, 1987, 53 (02) :65-69

[10] TREATMENT OF IMMUNE HEMOLYTIC-ANEMIA WITH GAMMA-GLOBULIN [J].

HARA, T ;

MIZUNO, Y ;

KAWANO, M ;

UEKI, Y ;

UEDA, K .

JOURNAL OF PEDIATRICS, 1987, 110 (05) :817-818