PATTERN-RECOGNITION OF P-31 MAGNETIC-RESONANCE SPECTROSCOPY TUMOR SPECTRA OBTAINED IN-VIVO

被引:24
作者
HOWELLS, SL [1 ]
MAXWELL, RJ [1 ]
HOWE, FA [1 ]
PEET, AC [1 ]
STUBBS, M [1 ]
RODRIGUES, LM [1 ]
ROBINSON, SP [1 ]
BALUCH, S [1 ]
GRIFFITHS, JR [1 ]
机构
[1] ST GEORGE HOSP, SCH MED, DIV BIOCHEM, CRC BIOMED MAGNET RESONANCE RES GRP, LONDON SW17 0RE, ENGLAND
关键词
D O I
10.1002/nbm.1940060402
中图分类号
Q6 [生物物理学];
学科分类号
071011 ;
摘要
Pattern recognition has been applied to the analysis of in vivo P-31 NMR spectra. Using four different classes of tumour and three types of normal tissue, cluster analysis and artificial neural networks were successful in separating and classifying the majority of samples analysed. Although the phosphomonoester and P(i) regions appeared to be the most important spectral features, data representing the entire P-31 spectrum were required for best separation of the tumour and tissue classes.
引用
收藏
页码:237 / 241
页数:5
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