CONSERVED SEQUENCE-TAGGED SITES - A PHYLOGENETIC APPROACH TO GENOME MAPPING

被引：21

作者：

MAZZARELLA, R

MONTANARO, V

KERE, J

REINBOLD, R

CICCODICOLA, A

DURSO, M

SCHLESSINGER, D

机构：

[1] WASHINGTON UNIV,SCH MED,DEPT MOLEC MICROBIOL,ST LOUIS,MO 63110

[2] WASHINGTON UNIV,SCH MED,CTR GENET MED,ST LOUIS,MO 63110

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1992年 / 89卷 / 09期

关键词：

PRIMATES; MOUSE; SEQUENCE CONSERVATION; EVOLUTION; PCR;

D O I：

10.1073/pnas.89.9.3681

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Cognate sites in genomes that diverged almost-equal-to 100 million years ago can be detected by PCR assays based on primer pairs from unique sequences. The great majority of such syntenically equivalent sequence-tagged sites (STSs) from human DNA can be used to assemble and format corresponding maps for other primates, and some based on gene sequences are shown to be useful for mouse and rat as well. Universal genomic mapping strategies may be possible by using sets of STSs common to any mammalian species.

引用

页码：3681 / 3685

页数：5

共 36 条

[1] YEAST ARTIFICIAL CHROMOSOMES CONTAINING HUMAN XQ24-XQ28 DNA - LIBRARY CONSTRUCTION AND REPRESENTATION OF PROBE SEQUENCES [J].