2-(TRIMETHYLSILYL)ETHYL GLYCOSIDES .8. SYNTHESIS OF THE MONODEOXY DERIVATIVES OF 2-(TRIMETHYLSILYL)ETHYL BETA-LACTOSIDE

被引：8

作者：

EKBERG, T ^{[1
]}

MAGNUSSON, G ^{[1
]}

机构：

[1] LUND UNIV,CTR CHEM,LUND INST TECHNOL,POB 124,S-22100 LUND,SWEDEN

来源：

CARBOHYDRATE RESEARCH | 1993年 / 246卷

关键词：

D O I：

10.1016/0008-6215(93)84028-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Monodeoxy derivatives of 2-(trimethylsilyl)ethyl (Me3SiEt) beta-lactoside were synthesized, by deoxygenation at the disaccharide level, for the 2'-, 3'-, 4'-, and 6'-monodeoxylactosides. The 2-, 3-, and 6-deoxy derivatives were synthesized by beta-D-galactosylation of suitably protected monodeoxygenated Me3SiEt glucosides. Silver silicate was shown to be an efficient glycosylation promoter in the preparation of the 2- and 3-deoxylactosides.

引用

页码：119 / 136

页数：18

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