IS MAN HELPLESS AGAINST CANCER - AN ENVIRONMENTAL APPROACH - ANTIMUTAGENIC AGENTS FROM EGYPTIAN FOOD AND MEDICINAL PREPARATIONS

被引：11

作者：

BADRIA, FA ^{[1
]}

机构：

[1] MANSOURA UNIV,FAC PHARM,DEPT PHARMACOGNOSY,MANSOURA 35511,EGYPT

来源：

CANCER LETTERS | 1994年 / 84卷 / 01期

关键词：

ANTIMUTAGENICITY; EGYPTIAN FOOD; HOST-MEDIATED ASSAY;

D O I：

10.1016/0304-3835(94)90351-4

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 [肿瘤学];

摘要：

Sixty-two Egyptian food and medicinal preparations were extensively examined for antimutagenic/anticarcinogenic activity using short-term and host-mediated assays. The antimutagenic activity of the substances examined was ranked as follows: thirteen (strong), seven (mild) and five (weak) after metabolic activation. Metabolic activation seems to be necessary for most antimutagenic substances in this study, e.g. radish inhibits 29% of mutagenicity produced in direct antimutagenic assay and inhibits 89% of mutagenicity induced in host-mediated assay.

引用

页码：1 / 5

页数：5

共 17 条

[1]

IMPROVED BACTERIAL TEST SYSTEM FOR DETECTION AND CLASSIFICATION OF MUTAGENS AND CARCINOGENS [J].

AMES, BN ;

LEE, FD ;

DURSTON, WE .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (03) :782-786

[2]

[Anonymous], 2012, FREE RADICALS BIOL

[3]

MECHANISMS OF INHIBITORS OF MUTAGENESIS AND CARCINOGENESIS - CLASSIFICATION AND OVERVIEW [J].

DEFLORA, S ;

RAMEL, C .

MUTATION RESEARCH, 1988, 202 (02) :285-306

[4]

DIGIOVANNI J, 1980, MODIFIERS CHEM CARCI, P145

[5]

ENOMOTO M, 1987, NATURALLY OCCURRING, P161

[6]

GAMBRIDGE MG, 1969, P SOC EXP BIOL MED, V130, P831

[7]

MUTATION INDUCTION IN CHINESE-HAMSTER V79 CELLS BY 2 VINYL-CHLORIDE METABOLITES, CHLOROETHYLENE OXIDE AND 2-CHLOROACETALDEHYDE [J].

HUBERMAN, E ;

BARTSCH, H ;

SACHS, L .

INTERNATIONAL JOURNAL OF CANCER, 1975, 16 (04) :639-644

[8]

HUBERMAN E, 1984, MUTATION CANCER MALF

[9]

KANAMORI H, 1984, CHEM PHARM BULL, V32, P2290

[10]

MUTAGENS AS CARCINOGENS - DEVELOPMENT OF CURRENT CONCEPTS [J].

LAWLEY, PD .

MUTATION RESEARCH, 1989, 213 (01) :3-25

← 1 2 →