BIOLOGY OF THE MONONUCLEAR PHAGOCYTE SYSTEM OF THE CENTRAL-NERVOUS-SYSTEM AND HIV-INFECTION

被引：41

作者：

PERRY, VH

LAWSON, LJ

REID, DM

机构：

[1] Department of Pharmacology, University of Oxford, Oxford OX1 3QT, Mansfield Rd.

来源：

JOURNAL OF LEUKOCYTE BIOLOGY | 1994年 / 56卷 / 03期

基金：

英国惠康基金;

关键词：

MACROPHAGE; MICROGLIA; CENTRAL NERVOUS SYSTEM; HIV;

D O I：

10.1002/jlb.56.3.399

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Infection of the central nervous system by HIV-1 results in widespread neuropathology and neurological symptoms. The cells infected in the brain belong to the mononuclear phagocyte lineage. We review aspects of the biology of the macrophage populations associated with the central nervous system and consider their distribution, phenotype, and kinetics in relation to HIV pathology

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页码：399 / 406

页数：8

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