MOLECULAR-CLONING OF HUMAN LIVER SULFITE OXIDASE

被引：50

作者：

GARRETT, RM ^{[1
]}

BELLISSIMO, DB ^{[1
]}

RAJAGOPALAN, KV ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT BIOCHEM,DURHAM,NC 27710

来源：

BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION | 1995年 / 1262卷 / 2-3期

关键词：

SULFITE OXIDASE; CDNA CLONING; SEQUENCE COMPARISON; (HUMAN LIVER);

D O I：

10.1016/0167-4781(95)00068-R

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A 2.4 kilobase cDNA clone of human sulfite oxidase was isolated from a human liver cDNA library in lambda gt10. Comparison of three sulfite oxidase sequences to several plant and fungal nitrate reductase sequences reveals a single conserved cysteine with highly conserved flanking sequences. The conserved cysteine is postulated to be a ligand of molybdenum in sulfite oxidase and nitrate reductase.

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页码：147 / 149

页数：3

相关论文

共 16 条

[1] THE USTILAGO-MAYDIS-NAR1 GENE ENCODING NITRATE REDUCTASE-ACTIVITY - SEQUENCE AND TRANSCRIPTIONAL REGULATION [J].

BANKS, GR ;

SHELTON, PA ;

KANUGA, N ;

HOLDEN, DW ;

SPANOS, A .

GENE, 1993, 131 (01) :69-78

[2]

BARBER MJ, 1990, J BIOL CHEM, V265, P20912

[3] SEQUENCE AND NITRATE REGULATION OF THE ARABIDOPSIS-THALIANA MESSENGER-RNA ENCODING NITRATE REDUCTASE, A METALLOFLAVOPROTEIN WITH 3 FUNCTIONAL DOMAINS [J].

CRAWFORD, NM ;

SMITH, M ;

BELLISSIMO, D ;

DAVIS, RW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (14) :5006-5010

[4] NITRATE REDUCTASE FROM SQUASH - CDNA CLONING AND NITRATE REGULATION [J].

CRAWFORD, NM ;

CAMPBELL, WH ;

DAVIS, RW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) :8073-8076

[5] CLONING AND ANALYSIS OF THE TOMATO NITRATE REDUCTASE-ENCODING GENE - PROTEIN DOMAIN-STRUCTURE AND AMINO-ACID HOMOLOGIES IN HIGHER-PLANTS [J].

DANIELVEDELE, F ;

DORBE, MF ;

CABOCHE, M ;

ROUZE, P .

GENE, 1989, 85 (02) :371-380

[6] SITE-DIRECTED MUTAGENESIS OF VIRTUALLY ANY PLASMID BY ELIMINATING A UNIQUE SITE [J].

DENG, WP ;

NICKOLOFF, JA .

ANALYTICAL BIOCHEMISTRY, 1992, 200 (01) :81-88

[7] SEQUENCE OF A CDNA-ENCODING THE BI-SPECIFIC NAD(P)H-NITRATE REDUCTASE FROM THE TREE BETULA-PENDULA AND IDENTIFICATION OF CONSERVED PROTEIN REGIONS [J].

FRIEMANN, A ;

BRINKMANN, K ;

HACHTEL, W .

MOLECULAR & GENERAL GENETICS, 1991, 227 (01) :97-105

[8]

GARRETT RM, 1994, J BIOL CHEM, V269, P272

[9]

JENSEN PE, 1993, U01029 GENB ACC

[10] PURIFICATION AND PROPERTIES OF SULFITE OXIDASE FROM HUMAN LIVER [J].

JOHNSON, JL ;

RAJAGOPALAN, KV .

JOURNAL OF CLINICAL INVESTIGATION, 1976, 58 (03) :543-550