CONCENTRATIONS OF ELEMENTS IN BRAIN-TUMORS

被引：7

作者：

ANDRASI, E ^{[1
]}

OROSZ, L ^{[1
]}

SCHEIBLER, H ^{[1
]}

BEZUR, L ^{[1
]}

ERNYEI, L ^{[1
]}

机构：

[1] TECH UNIV BUDAPEST, INST GEN & ANALYT CHEM, H-1111 BUDAPEST, HUNGARY

来源：

MIKROCHIMICA ACTA | 1995年 / 118卷 / 1-2期

关键词：

TRACE ELEMENTS; NORMAL HUMAN BRAIN; BRAIN TUMORS; INAA; ICP-AES;

D O I：

10.1007/BF01242234

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The aim of our experiments was to investigate the possible elemental concentration changes in brain tumours (glioblastoma multiforme). Our project also incorporated the determination of the regional distribution of elements in normal human brains. 17 elements (Na, K, Ca, Mg, Fe, P, S, Al, B, Ba, Co, Cr, Ni, Mn, Pb, Sr, Zn) have been measured in 21 different regions of 20 normal brains and in clinically and histopathologically selected brain regions of patients with brain tumours. Analyses were carried out by instrumental neutron activation analysis (INAA) and inductively coupled plasma atomic emission spectrometry (ICP-AES). Quality control was ensured by using NBS Bovine Liver 1577a standard reference material. Comparison between the healthy and brain tumour concentration data using statistical evaluation revealed only a few elements (e.g. B, Zn, Sr) which showed significant differences as a consequence of the brain tumour.

引用

页码：113 / 121

页数：9

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