STEREOSELECTIVE BINDING OF NIGULDIPINE ENANTIOMERS TO ALPHA-1A-ADRENOCEPTORS LABELED WITH [H-3] 5-METHYL-URAPIDIL

被引：42

作者：

GRAZIADEI, I

ZERNIG, G

BOER, R

GLOSSMAN, H

机构：

[1] INST BIOCHEM PHARMACOL, PETER MAYRSTR 1, A-6020 INNSBRUCK, AUSTRIA

[2] BYK GULDEN LOMBERG GMBH, D-7750 CONSTANCE, GERMANY

来源：

EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION | 1989年 / 172卷 / 4-5期

关键词：

D O I：

10.1016/0922-4106(89)90013-8

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：329 / 337

页数：9

共 19 条

[1] (+)-NIGULDIPINE BINDS WITH VERY HIGH-AFFINITY TO CA-2+ CHANNELS AND TO A SUBTYPE OF ALPHA-1-ADRENOCEPTORS [J].

BOER, R ;

GRASSEGGER, A ;

SCHUDT, C ;

GLOSSMANN, H .

EUROPEAN JOURNAL OF PHARMACOLOGY-MOLECULAR PHARMACOLOGY SECTION, 1989, 172 (02) :131-145

[2] H-3-TVX Q-7821 - IDENTIFICATION OF 5-HT1 BINDING-SITES AS TARGET FOR A NOVEL PUTATIVE ANXIOLYTIC [J].

DOMPERT, WU ;

GLASER, T ;

TRABER, J .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1985, 328 (04) :467-470

[3] INVESTIGATIONS ON THE MODE OF ACTION OF A NEW ANTIHYPERTENSIVE DRUG, URAPIDIL, IN THE ISOLATED RAT VAS-DEFERENS [J].

ELTZE, M .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1979, 59 (1-2) :1-9

[4]

Emmelot P, 1974, Methods Enzymol, V31, P75

[5]

FOZARD J R, 1987, British Journal of Pharmacology, V90, p24P

[6] HYPOTENSIVE EFFECT OF URAPIDIL - CNS SITE AND RELATIVE CONTRIBUTION [J].

GILLIS, RA ;

DRETCHEN, KL ;

NAMATH, I ;

ANASTASI, N ;

SOUZA, JD ;

HILL, K ;

BROWNE, RK ;

QUEST, JA .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1987, 9 (01) :103-109

[7]

GLOSSMANN H, 1985, METHOD ENZYMOL, V109, P513

[8] 5-METHYL-URAPIDIL DISCRIMINATES BETWEEN SUBTYPES OF THE ALPHA-1-ADRENOCEPTOR [J].

GROSS, G ;

HANFT, G ;

RUGEVICS, C .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 151 (02) :333-335

[9] URAPIDIL AND SOME ANALOGS WITH HYPOTENSIVE PROPERTIES SHOW HIGH AFFINITIES FOR 5-HYDROXYTRYPTAMINE (5-HT) BINDING-SITES OF THE 5-HT1A SUBTYPE AND FOR ALPHA-1-ADRENOCEPTOR BINDING-SITES [J].

GROSS, G ;

HANFT, G ;

KOLASSA, N .

NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1987, 336 (06) :597-601

[10] ALPHA-1-ADRENOCEPTOR SUBTYPES LINKED TO DIFFERENT MECHANISMS FOR INCREASING INTRACELLULAR CA-2+ IN SMOOTH-MUSCLE [J].

HAN, C ;

ABEL, PW ;

MINNEMAN, KP .

NATURE, 1987, 329 (6137) :333-335

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