DIPHENYL (2,3-DIHYDRO-2-THIOXO-3-BENZOXAZOLYL)PHOSPHONATE - A NEW, REACTIVE CONDENSING AGENT FOR THE SYNTHESIS OF AMIDES, ESTERS, PEPTIDES, AND BETA-LACTAMS VIA CONDENSATION

被引：22

作者：

UEDA, M

MORI, H

机构：

[1] Dept. Materials Science/Engineering, Faculty of Engineering, Yamagata University

来源：

BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN | 1992年 / 65卷 / 06期

关键词：

D O I：

10.1246/bcsj.65.1636

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Diphenyl (2,3-dihydro-2-thioxo-3-benzoxazolyl)phosphonate (1) prepared from 2-benzoxazolethiol and diphenyl phosphorochloridate was proved to be a very useful condensing agent. A variety of amides, esters, and dipeptides were obtained in excellent yields. Furthermore, this reagent was successfully applied to the synthesis of beta-lactams from beta-amino acids.

引用

页码：1636 / 1641

页数：6

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