RAMAN-SPECTRA OF HUMAN KERATOTIC BIOPOLYMERS - SKIN, CALLUS, HAIR AND NAIL

被引:112
作者
WILLIAMS, AC
EDWARDS, HGM
BARRY, BW
机构
[1] Postgraduate Studies in Pharmaceutical Technology, School of Pharmacy, University of Bradford, Bradford, West Yorkshire
[2] University of Bradford, Bradford, West Yorkshire
[3] Postgraduate Studies in Pharmaceutical Technology, School of Pharmacy, University of Bradford, Bradford, West Yorkshire
关键词
D O I
10.1002/jrs.1250250113
中图分类号
O433 [光谱学];
学科分类号
0703 ; 070302 ;
摘要
Fourier transform Raman spectra of human keratotic biopolymers were obtained. The spectra from skin stratum corneum, callus, nail and hair were fluorescence free and the samples did not degrade during analysis. Assignments consistent with the vibrational wavenumbers were made to characterize the molecular and conformational nature of the samples. The principal structural dissimilarities were in the sulphur content of tissues containing hard keratin (hair and nail) and soft keratin (stratum corneum and callus).
引用
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页码:95 / 98
页数:4
相关论文
共 14 条
[1]  
Barry, 1983, DERMATOLOGICAL FORMU
[2]   FOURIER-TRANSFORM RAMAN AND IR-SPECTRA OF SNAKE SKIN [J].
BARRY, BW ;
WILLIAMS, AC ;
EDWARDS, HGM .
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY, 1993, 49 (5-6) :801-807
[3]   FOURIER-TRANSFORM RAMAN AND INFRARED VIBRATIONAL STUDY OF HUMAN SKIN - ASSIGNMENT OF SPECTRAL BANDS [J].
BARRY, BW ;
EDWARDS, HGM ;
WILLIAMS, AC .
JOURNAL OF RAMAN SPECTROSCOPY, 1992, 23 (11) :641-645
[4]  
DAWBER RPR, 1985, METHODS SKIN RES, P329
[5]   EPIDERMAL LIPIDS, MEMBRANES, AND KERATINIZATION [J].
ELIAS, PM .
INTERNATIONAL JOURNAL OF DERMATOLOGY, 1981, 20 (01) :1-19
[6]  
FORSLIND B, 1970, ACTA DERM-VENEREOL, V50, P161
[7]   EFFECTS OF FREEZING ON HUMAN-SKIN PERMEABILITY [J].
HARRISON, SM ;
BARRY, BW ;
DUGARD, PH .
JOURNAL OF PHARMACY AND PHARMACOLOGY, 1984, 36 (04) :261-262
[8]  
KLIGMAN AM, 1963, ARCH DERMATOL, V88, P70
[9]  
Mercer E. H., 1958, BIOLOGY HAIR GROWTH, P113
[10]   DRUG PERMEATION THROUGH HUMAN SKIN - THEORY AND INVITRO EXPERIMENTAL MEASUREMENT [J].
MICHAELS, AS ;
CHANDRASEKARAN, SK ;
SHAW, JE .
AICHE JOURNAL, 1975, 21 (05) :985-996