MEGESTROL-ACETATE FOR ANOREXIA AND CACHEXIA

被引:19
作者
LOPRINZI, CL
JOHNSON, PA
JENSEN, M
机构
[1] MAYO CLIN & MAYO FDN,DEPT MED,ROCHESTER,MN 55905
[2] CARLE CLIN ASSOC,DEPT ONCOL,URBANA,IL
关键词
MEGESTROL ACETATE; ANOREXIA CACHEXIA;
D O I
10.1159/000227128
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Based on promising preliminary information obtained from uncontrolled pilot studies, several randomized, placebo-controlled, double-blind clinical trials have been launched to evaluate the effectiveness of megestrol acetate for the treatment of patients with anorexia and/or cachexia. The results of these studies have demonstrated that megestrol acetate can improve patients' appetites and promote nonfluid weight gain in some. They also suggest that megestrol acetate has antiemetic properties. Ongoing clinical trials are evaluating the dose-response relationship of megestrol acetate for these clinical problems and whether megestrol acetate will improve the survival of patients at risk for developing cancer anorexia/cachexia.
引用
收藏
页码:46 / 49
页数:4
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