The coelomic cavity - A reservoir for metals

被引：14

作者：

Wathen, NC

Delves, HT

Campbell, DJ

Chard, T

机构：

[1] ST BARTHOLOMEWS HOSP,DEPT GYNAECOL,LONDON EC1A 7BE,ENGLAND

[2] ST BARTHOLOMEWS HOSP,DEPT REPROD PHYSIOL,LONDON EC1A 7BE,ENGLAND

[3] SOUTHAMPTON GEN HOSP,FAC MED,TRACE ELEMENT UNIT,SOUTHAMPTON SO9 4XY,HANTS,ENGLAND

来源：

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY | 1995年 / 173卷 / 06期

关键词：

metals; pregnancy; amniotic fluid; extraembryonic coelom;

D O I：

10.1016/0002-9378(95)90446-8

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

OBJECTIVE: The concentrations of metals in fluids surrounding the first-trimester fetus were measured. STUDY DESIGN: Atomic absorption spectrometry was used to measure concentrations of metals in matched samples of amniotic and extraembryonic coelomic fluids in 17 women between 9 and 12 weeks of pregnancy. RESULTS: Concentrations of calcium, magnesium, iron, copper, and manganese (but not zinc, cadmium, or lead) were significantly higher in coelomic than in amniotic fluid. There was no significant difference between levels of iron, manganese, and lead in controls and amniotic fluid or between concentrations of manganese, cadmium, and lead in controls and coelomic fluid. There was no relationship between the concentrations of each metal in amniotic and coelomic fluid. CONCLUSION: The extraembryonic coelom is an important site of concentration of metals in early pregnancy. This might represent a store of metals essential for normal embryonic and fetal development or constitute a defense mechanism against environmental conditions adverse to the fetus.

引用

页码：1884 / 1888

页数：5

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