A COMPARISON OF RUBAZYME-M AND MACRIA FOR THE DETECTION OF RUBELLA-SPECIFIC IGM

被引：20

作者：

BEST, JM

PALMER, SJ

MORGANCAPNER, P

HODGSON, J

机构：

[1] ST THOMAS HOSP, SCH MED, DEPT VIROL, LONDON SE1 7EH, ENGLAND

[2] UNIV LONDON KINGS COLL HOSP, SCH MED, DEPT MICROBIOL, LONDON SE5 8RX, ENGLAND

来源：

JOURNAL OF VIROLOGICAL METHODS | 1984年 / 8卷 / 1-2期

关键词：

D O I：

10.1016/0166-0934(84)90044-2

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Carefully selected [human] sera, 186, were tested for rubella-specific IgM by Rubazyme-M (Abbott Diagnostics) and an M-antibody capture radioimmunoassay (MACRIA). Of these sera, 11 were from cases of infectious mononucleosis, 6 of which gave positive results in MACRIA, while 1 gave a positive result in Rubazyme-M. Of the remaining 175 sera, 158 gave concordant results while 17 sera gave discordant results; these 17 were also tested by serum fractionation. Problems were encountered with all assay systems used. It is therefore recommended that the results of all tests for rubella-specific IgM should be interpreted with caution.

引用

页码：99 / 109

页数：11

共 8 条

[1]

ALNAKIB W, 1975, LANCET, V1, P182

[2]

BEST JM, 1969, LANCET, V2, P65

[3] RUBELLA-SPECIFIC IGM REACTIVITY IN SERA FROM CASES OF INFECTIOUS MONONUCLEOSIS [J].