A SHORT STEREOCONTROLLED SYNTHESIS OF LEUKOTRIENE-B4

被引：47

作者：

CHEMIN, D

LINSTRUMELLE, G

机构：

[1] UR 402 de CNRS, Labortoire de Chimie, Ecole Normale Supérieure, 75231 Paris Cedex 05

来源：

TETRAHEDRON | 1992年 / 48卷 / 10期

关键词：

D O I：

10.1016/S0040-4020(01)88516-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A short convergent total synthesis of LTB4 1 is accomplished by an efficient palladium-catalyzed coupling reaction of two easily accessible chiral synthons 3 and 4.

引用

页码：1943 / 1952

页数：10

共 24 条

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[2] AN EFFICIENT SYNTHESIS OF LEUKOTRIENE-B4
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[3] TOTAL SYNTHESIS OF (+)-LEUKOTRIENE B4 METHYL-ESTER AND ITS 5-EPIMER FROM (R)-GLYCIDOL
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[4] STEREOSPECIFIC SYNTHESES AND SPECTROSCOPIC PROPERTIES OF ISOMERIC 2,4,6,8-UNDECATETRAENES - NEW HYDROCARBONS FROM THE MARINE BROWN ALGA-GIFFORDIA-MITCHELLAE .4.
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[5] CATALYTIC-HYDROGENATION .6. REACTION OF SODIUM-BOROHYDRIDE WITH NICKEL SALTS IN ETHANOL SOLUTION - P-2 NICKEL, A HIGHLY CONVENIENT, NEW, SELECTIVE HYDROGENATION CATALYST WITH GREAT SENSITIVITY TO SUBSTRATE STRUCTURE
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[6] PROTON MAGNETIC-RESONANCE SPECTRA OF LEUKOTRIENE-A METHYL ESTER(I), LEUKOTRIENE-B METHYL-ESTER DIACETATE(II) AND 12-EPI-6-E,8-Z-LEUKOTRIENE-B METHYL-ESTER DIACETATE(III,5-S,12-S-DI-HETE)
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[7] LEUKOTRIENE-B - TOTAL SYNTHESIS AND ASSIGNMENT OF STEREOCHEMISTRY
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[8] A STEREOCONTROLLED AND EFFECTIVE SYNTHESIS OF LEUKOTRIENE-B-(1)
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[J]. TETRAHEDRON LETTERS, 1981, 22 (12) : 1077 - 1080
[9] STEREOSELECTIVE SYNTHESIS OF POLYENIC ALCOHOLS - A NEW ROUTE TO THE LEUKOTRIENES-B
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[J]. TETRAHEDRON LETTERS, 1986, 27 (48) : 5857 - 5860
[10] STEREOSPECIFIC SYNTHESIS OF LEUKOTRIENE B4 (LTB4)
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[J]. TETRAHEDRON LETTERS, 1982, 23 (07) : 739 - 742

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