PATHOGENETIC MECHANISMS OF FETAL AKINESIA DEFORMATION SEQUENCE AND OLIGOHYDRAMNIOS SEQUENCE

被引：39

作者：

RODRIGUEZ, JI ^{[1
]}

PALACIOS, J ^{[1
]}

机构：

[1] HOSP LA PAZ, DEPT PATHOL, MADRID, SPAIN

来源：

AMERICAN JOURNAL OF MEDICAL GENETICS | 1991年 / 40卷 / 03期

关键词：

DEFORMATION SEQUENCES; FETAL AKINESIA; OLIGOHYDRAMNIOS;

D O I：

10.1002/ajmg.1320400307

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

This article briefly reviews the participation of fetal compression, muscular weakness, and fetal akinesia in the genesis of the anomalies found in fetal akinesia deformation sequence (FADS) and oligohydramnios sequence (OS). Both sequences share phenotypic manifestations, such as arthrogryposis, short umbilical cord, and lung hypoplasia, in relation to decreased intrauterine fetal motility. Other characteristic manifestations found in OS, such as Potter face, and redundant skin, are produced by fetal compression. On the other hand, growth retardation, craniofacial anomalies, micrognathia, long bone hypoplasia, and polyhydramnios found in FADS could be related to intrauterine muscular weakness.

引用

页码：284 / 289

页数：6

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