QUANTITATIVE STRUCTURE EXTRACTION RELATIONSHIPS - A MODEL FOR SUPERCRITICAL-FLUID EXTRACTION

被引：10

作者：

KANE, M

DEAN, JR

HITCHEN, SM

TOMLINSON, WR

TRANTER, RL

DOWLE, CJ

机构：

[1] UNIV NORTHUMBRIA,DEPT CHEM & LIFE SCI,ELLISON BLDG,NEWCASTLE TYNE NE1 8ST,ENGLAND

[2] GLAXO MFG SERV,BARNARD CASTLE DL12 8DT,DURHAM,ENGLAND

[3] ICI PLC,WILTON RES CTR,MIDDLESBROUGH TS6 8JE,CLEVELAND,ENGLAND

来源：

ANALYST | 1993年 / 118卷 / 10期

关键词：

SUPERCRITICAL FLUID EXTRACTION; SOLUBILITY PARAMETER; HYDROPHOBICITY; PARTITION COEFFICIENT; MOLECULAR STRUCTURE;

D O I：

10.1039/an9931801261

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A rapid method for predicting the solubility of an analyte in supercritical carbon dioxide is reported. The method is based on determining the hydrophobic interaction and the solubility parameter from easily obtained constants. The simplicity of the method is demonstrated with respect to a group of substituted benzophenones. Hydrophobicity is derived from log P values as determined by the Hansch-Leo method, whereas the solubility parameter is determined by the method of Fedors. Multilinear regression has indicated a direct correlation between the amount of analyte extracted, expressed as the mole fraction, and the log P/solubility parameters.

引用

页码：1261 / 1264

页数：4

共 19 条

[1] SUPERCRITICAL FLUID EXTRACTION FOR THE RAPID-DETERMINATION OF POLYCHLORINATED DIBENZO-PARA-DIOXINS AND DIBENZOFURANS IN MUNICIPAL INCINERATOR FLY-ASH [J].