STIMULATION OF NERVE GROWTH-FACTOR PRODUCTION BY PYRROLOQUINOLINE QUINONE AND ITS DERIVATIVES IN-VITRO AND IN-VIVO

被引：60

作者：

YAMAGUCHI, K

SASANO, A

URAKAMI, T

TSUJI, T

KONDO, K

机构：

[1] SAGAMI CHEM RES CTR, SAGAMIHARA, KANAGAWA 229, JAPAN

[2] MISTUBISHI GAS CHEM CO LTD, DIV BIOCHEM, MINATO KU, TOKYO 105, JAPAN

来源：

BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 1993年 / 57卷 / 07期

关键词：

D O I：

10.1271/bbb.57.1231

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Pyrroloquinoline quinone (PQQ), which is a cofactor of microbial quinoprotein enzymes, was found to be a potent enhancer of nerve growth factor (NGF) production in vitro. One of PQQ derivatives, oxazopyrroloquinoline trimethylester, had little activity in vitro, but increased the NGF content in rat brain in vivo.

引用

页码：1231 / 1233

页数：3

共 21 条

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