HABITUATION OF AN INVERTEBRATE ESCAPE REFLEX DUE TO MODULATION BY HIGHER CENTERS RATHER THAN LOCAL EVENTS

被引：55

作者：

KRASNE, FB ^{[1
]}

TESHIBA, TM ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,BRAIN RES INST,LOS ANGELES,CA 90024

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1995年 / 92卷 / 08期

关键词：

CRAYFISH; LATERAL GIANT FIBER; LEARNING; SYNAPTIC PLASTICITY; INHIBITION;

D O I：

10.1073/pnas.92.8.3362

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Learning is widely thought to result from altered potency of synapses within the neural pathways that mediate the learned behavior. Support for this belief, which pervades current physiological and computational thinking, comes especially from the analysis of cases of simple learning in invertebrates. Here, evidence is presented that in one such case, habituation of crayfish escape, the learning is more due to onset of;tonic descending inhibition than to the intrinsic depression of circuit synapses to which it was previously attributed. Thus, the altered performance seems to depend at least as much on events in higher centers as on local plasticity.

引用

页码：3362 / 3366

页数：5

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