APPARENT OUTBREAKS OF CLOSTRIDIUM-DIFFICILE-ASSOCIATED DIARRHEA IN HORSES IN A VETERINARY MEDICAL TEACHING HOSPITAL

被引：79

作者：

MADEWELL, BR ^{[1
]}

TANG, YJ ^{[1
]}

JANG, S ^{[1
]}

MADIGAN, JE ^{[1
]}

HIRSH, DC ^{[1
]}

GUMERLOCK, PH ^{[1
]}

SILVA, J ^{[1
]}

机构：

[1] UNIV CALIF DAVIS,SCH MED,DEPT INTERNAL MED,CANC & MOLEC RES LAB,DAVIS,CA 95616

来源：

JOURNAL OF VETERINARY DIAGNOSTIC INVESTIGATION | 1995年 / 7卷 / 03期

关键词：

D O I：

10.1177/104063879500700308

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Intestinal colonization with toxigenic strains of Clostridium difficle was documented in 9 of 10 horses with acute onset diarrhea in a veterinary medical teaching hospital, whereas a similar isolate was detected in only 1 of 23 other horses without diarrhea in the hospital. One horse with diarrhea was infected simultaneously with both C. difficile and Salmonella krefeld. Clostridium difficile was detected by fecal culture on selective medium, confirmed with a latex particle agglutination test, and identified as toxigenic by polymerase chain reaction amplification of toxin A and toxin B gene sequences. Using an arbitrarily-primed polymerase chain reaction, 6 distinct C. difficile isolates were detected in the feces of the 9 affected horses at the time of the outbreak of diarrhea.

引用

页码：343 / 346

页数：4

共 23 条

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