INVOLVEMENT OF SMALL-INTESTINAL MOTILITY IN BLOOD-GLUCOSE RESPONSE TO DIETARY FIBER IN MAN

被引:49
作者
CHERBUT, C [1 ]
DESVARANNES, SB [1 ]
SCHNEE, M [1 ]
RIVAL, M [1 ]
GALMICHE, JP [1 ]
DELORTLAVAL, J [1 ]
机构
[1] HOP G&R LAENNEC,EQUIPE FONCT DIGEST & NUTR,NANTES,FRANCE
关键词
DIETARY FIBER; GLYCEMIA; ELECTROMYOGRAPHY; INTESTINAL MOTILITY; MAN;
D O I
10.1079/BJN19940175
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
Three dietary fibres with different physicochemical properties were studied in healthy humans for their effects on small intestinal motility and postprandial hyperglycaemia. Duodeno-jejunal motor activity was evaluated electromyographically for 180 min in six subjects who had ingested a test meal composed of glucose alone or glucose with 15 g of wheat bran (WB), sugar beet (SB) or ispaghula (I) fibres. Glucose and insulin concentrations were determined during the same period. Each subject received each of the four test meals randomly during a 4 d period. Addition of SB or I to the glucose meal altered duodeno-jejunal motility. Both of these fibres inhibited stationary contractile activity and increased the propagation length and velocity of propagated activity, whereas addition of WB had no effect. These results could reflect the high water-holding capacity of SB and I. Blood glycaemic response to the glucose meal was reduced by SB and I but remained unchanged with WB. Postprandial blood glucose levels were significantly correlated with the total motility index (r 0.82) and stationary activity (r 0.79). Taken together, these observations suggest that the contractile activity induced by dietary fibre in the small intestine probably plays a major role in delayed glucose absorption.
引用
收藏
页码:675 / 685
页数:11
相关论文
共 34 条
[1]   DIETARY FIBER - INVITRO METHODS THAT ANTICIPATE NUTRITION AND METABOLIC-ACTIVITY IN HUMANS [J].
ADIOTOMRE, J ;
EASTWOOD, MA ;
EDWARDS, CA ;
BRYDON, WG .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1990, 52 (01) :128-134
[2]   OAT GUM LOWERS GLUCOSE AND INSULIN AFTER AN ORAL GLUCOSE-LOAD [J].
BRAATEN, JT ;
WOOD, PJ ;
SCOTT, FW ;
RIEDEL, KD ;
POSTE, LM ;
COLLINS, MW .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1991, 53 (06) :1425-1430
[3]   THE EFFECT OF GUAR GUM ON THE DISTRIBUTION OF A RADIOLABELED MEAL IN THE GASTROINTESTINAL-TRACT OF THE RAT [J].
BROWN, NJ ;
WORLDING, J ;
RUMSEY, RDE ;
READ, NW .
BRITISH JOURNAL OF NUTRITION, 1988, 59 (02) :223-231
[4]  
BUENO L, 1981, GASTROENTEROLOGY, V80, P701
[5]   ACTION OF GUAR GUMS ON THE VISCOSITY OF DIGESTIVE CONTENTS AND ON THE GASTROINTESTINAL MOTOR FUNCTION IN PIGS [J].
CHERBUT, C ;
ALBINA, E ;
CHAMP, M ;
DOUBLIER, JL ;
LECANNU, G .
DIGESTION, 1990, 46 (04) :205-213
[6]   Dietary fibre effects on intestinal transit in man: involvement of their physicochemical and fermentative properties [J].
Cherbut, C. ;
Salvador, V. ;
Barry, J. -L. ;
Doulay, F. ;
Delort-Laval, J. .
FOOD HYDROCOLLOIDS, 1991, 5 (1-2) :15-22
[7]  
Cummings J. H., 1978, Journal of Plant Foods, V3, P83
[8]  
DESVARANNES SB, 1992, EUR J GASTROEN HEPAT, V4, P539
[9]   PHYSICAL-PROPERTIES OF DIETARY FIBER THAT INFLUENCE PHYSIOLOGICAL-FUNCTION - A MODEL FOR POLYMERS ALONG THE GASTROINTESTINAL-TRACT [J].
EASTWOOD, MA ;
MORRIS, ER .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1992, 55 (02) :436-442
[10]   MEASUREMENT OF WATER-HOLDING PROPERTIES OF FIBER AND THEIR FECAL BULKING ABILITY IN MAN [J].
EASTWOOD, MA ;
ROBERTSON, JA ;
BRYDON, WG ;
MACDONALD, D .
BRITISH JOURNAL OF NUTRITION, 1983, 50 (03) :539-547