Mesh nebulizers have become the first choice for new nebulized pharmaceutical drug developments

被引:108
作者
Pritchard, John N. [1 ]
Hatley, Ross H. M. [1 ]
Denyer, John [2 ]
von Hollen, Dirk [3 ]
机构
[1] Respiron Resp Drug Delivery UK Ltd, Chichester, W Sussex, England
[2] PS5 Consultants Ltd, Portsmouth, Hants, England
[3] Respironics Inc, Murrysville, PA USA
关键词
clinical trial registrations; manufacture; market uptake; mesh/jet; nebulizer; popularity;
D O I
10.4155/tde-2017-0102
中图分类号
R9 [药学];
学科分类号
1007 [药学];
摘要
In the 24 years since first being marketed, the mesh nebulizer has been developed by five main manufacturers into a viable solution for the delivery of high-value nebulized drugs. Mesh nebulizers provide increased portability, convenience and energy efficiency along with similar lung deposition and increased ease of use compared with jet nebulizers. An analysis of EU and US clinical trial databases has shown that mesh nebulizers are now preferred over jet nebulizers for clinical trials sponsored by pharmaceutical companies. The results show a strong preference for the use of mesh nebulizers in trials involving high cost and niche therapy areas. Built-in capability to optimize the way patients use their mesh nebulizer and manage their disease will further increase uptake.
引用
收藏
页码:121 / 136
页数:16
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