RETINAL ISCHEMIA INDUCED BY OCCLUSION OF BOTH COMMON CAROTID ARTERIES IN RATS AS DEMONSTRATED BY ELECTRORETINOGRAPHY

被引：56

作者：

BLOCK, F ^{[1
]}

SCHWARZ, M ^{[1
]}

SONTAG, KH ^{[1
]}

机构：

[1] MAX PLANCK INST EXPTL MED,W-3400 GOTTINGEN,GERMANY

来源：

NEUROSCIENCE LETTERS | 1992年 / 144卷 / 1-2期

关键词：

RETINAL ISCHEMIA; ELECTRORETINOGRAM; RAT;

D O I：

10.1016/0304-3940(92)90731-L

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In 2 models of reduced cerebral blood flow permanent occlusion of the vertebral arteries plus transient occlusion of the common carotid arteries (4VO) and transient clamping of the common carotid arteries (BCCA) the acute effects on the electrical function of the retina were monitored by recording the photopic electroretinogram. During both 4VO and BCCA the amplitude of the b-wave was reduced. Within 30 min of reperfusion after 4VO and after BCCA the b-wave had fully recovered. In contrast, the a-wave was not affected by either treatment. The data suggest that occlusion of common carotid arteries leads to retinal ischemia and might represent a useful model of amaurosis fugax.

引用

页码：124 / 126

页数：3

共 17 条

[1]

BLOCK F, 1990, PHARMACOLOGY OF CEREBRAL ISCHEMIA 1990, P47

[2] EFFECTS OF BILATERAL CLAMPING OF CAROTID ARTERIES ON HIPPOCAMPAL KINDLING IN RATS [J].