INTERCOLONY VARIATION IN FLUID BALANCE AND ITS RELATIONSHIP TO VASOPRESSIN SECRETION IN MALE SPRAGUE-DAWLEY RATS

被引：7

作者：

WELLS, T ^{[1
]}

WINDLE, RJ ^{[1
]}

PEYSNER, K ^{[1
]}

FORSLING, ML ^{[1
]}

机构：

[1] UNITED MED & DENT SCH GUYS & ST THOMAS HOSP,ST THOMASS HOSP,SCH MED,DEPT OBSTET & GYNAECOL,LONDON SE1 7EH,ENGLAND

来源：

LABORATORY ANIMALS | 1993年 / 27卷 / 01期

关键词：

INTERCOLONY VARIATION; SPRAGUE-DAWLEY RATS; FLUID BALANCE; VASOPRESSIN; SEMIBARRIER SYSTEM;

D O I：

10.1258/002367793781082395

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Salt and water balance and vasopressin secretion were measured in three colonies of Sprague-Dawley rats. Although sodium and water retention were similar between the groups, there were marked differences in both the rate and diurnal pattern of intake and excretion. Animals housed under semi-barrier conditions showed a lower basal plasma vasopressin concentration but were more sensitive to physiological stimuli. However, since pathogenic status and environmental conditions cannot entirely explain these results, genetic variation is likely to be a contributory factor.

引用

页码：40 / 46

页数：7

共 22 条

[1] CHANGES IN WATER AND ELECTROLYTE BALANCE, PLASMA-VOLUME AND COMPOSITION DURING PREGNANCY IN THE RAT [J].