NUCLEOTIDES .32. SYNTHESIS OF 2'-5' CONNECTED OLIGONUCLEOTIDES - PRODRUGS FOR ANTIVIRAL AND ANTITUMORAL NUCLEOSIDES

被引：21

作者：

HERDEWIJN, P

CHARUBALA, R

DECLERCQ, E

PFLEIDERER, W

机构：

[1] UNIV CONSTANCE,FAK CHEM,W-7750 CONSTANCE,GERMANY

[2] CATHOLIC UNIV LEUVEN,REGA INST MED RES,10 MINDERBROEDERSST,B-3000 LOUVAIN,BELGIUM

来源：

HELVETICA CHIMICA ACTA | 1989年 / 72卷 / 08期

关键词：

D O I：

10.1002/hlca.19890720811

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：1739 / 1748

页数：10

共 12 条

[1]

BALZARINI J, 1987, MOL PHARMACOL, V32, P410

[2]

CHARUBALA R, 1981, LIEBIGS ANN CHEM, P2392

[3] BIOCHEMICAL ASPECTS OF THE SELECTIVE ANTIHERPES ACTIVITY OF NUCLEOSIDE ANALOGS [J].

DECLERCQ, E .

BIOCHEMICAL PHARMACOLOGY, 1984, 33 (14) :2159-2169

[4]

DECLERCQ E, 1987, MOL PHARMACOL, V32, P286

[5] COMPARATIVE EFFICACY OF ANTIHERPES DRUGS AGAINST DIFFERENT STRAINS OF HERPES-SIMPLEX VIRUS [J].

DECLERCQ, E ;

DESCAMPS, J ;

VERHELST, G ;

WALKER, RT ;

JONES, AS ;

TORRENCE, PF ;

SHUGAR, D .

JOURNAL OF INFECTIOUS DISEASES, 1980, 141 (05) :563-574

[6] PHOSPHORYLATION OF 3'-AZIDO-3'-DEOXYTHYMIDINE AND SELECTIVE INTERACTION OF THE 5'-TRIPHOSPHATE WITH HUMAN-IMMUNODEFICIENCY-VIRUS REVERSE-TRANSCRIPTASE [J].

FURMAN, PA ;

FYFE, JA ;

STCLAIR, MH ;

WEINHOLD, K ;

RIDEOUT, JL ;

FREEMAN, GA ;

LEHRMAN, SN ;

BOLOGNESI, DP ;

BRODER, S ;

MITSUYA, H ;

BARRY, DW .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) :8333-8337

[7] NUCLEOTIDES .31. MODIFIED OLIGOMERIC 2'-5' A ANALOGS - SYNTHESIS OF 2'-5' OLIGONUCLEOTIDES WITH 9-(3'-AZIDO-3'-DEOXY-BETA-D-XYLOFURANOSYL)ADENINE AND 9-(3'-AMINO-3'-DEOXY-BETA-D-XYLOFURANOSYL)ADENINE AS MODIFIED NUCLEOSIDES [J].

HERDEWIJN, P ;

CHARUBALA, R ;

PFLEIDERER, W .

HELVETICA CHIMICA ACTA, 1989, 72 (08) :1729-1738

[8] THE PARA-NITROPHENYLETHYL (NPE) GROUP - A VERSATILE NEW BLOCKING GROUP FOR PHOSPHATE AND AGLYCONE PROTECTION IN NUCLEOSIDES AND NUCLEOTIDES [J].

HIMMELSBACH, F ;

SCHULZ, BS ;

TRICHTINGER, T ;

CHARUBALA, R ;

PFLEIDERER, W .

TETRAHEDRON, 1984, 40 (01) :59-72

[9] SYNTHESIS AND BIOLOGICAL PROPERTIES OF SOME CYCLIC PHOSPHOTRIESTERS DERIVED FROM 2'-DEOXY-5-FLUOROURIDINE [J].

HUNSTON, RN ;

JONES, AS ;

MCGUIGAN, C ;

WALKER, RT ;

BALZARINI, J ;

DECLERCQ, E .

JOURNAL OF MEDICINAL CHEMISTRY, 1984, 27 (04) :440-444

[10] CHEMICAL SYNTHESIS OF OLIGO-NUCLEOTIDES AND POLY-NUCLEOTIDES BY PHOSPHOTRIESTER APPROACH [J].

REESE, CB .

TETRAHEDRON, 1978, 34 (21) :3143-3179

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