PRIMARY STRUCTURE OF TORPEDO-MARMORATA CHLORIDE CHANNEL ISOLATED BY EXPRESSION CLONING IN XENOPUS OOCYTES

被引：451

作者：

JENTSCH, TJ

STEINMEYER, K

SCHWARZ, G

机构：

[1] Centre for Molecular Neurobiology (ZMNH), Hamburg University, D-2000 Hamburg 20

来源：

NATURE | 1990年 / 348卷 / 6301期

关键词：

D O I：

10.1038/348510a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A complementary DNA encoding a voltage-gated chloride channel from Torpedo marmorata electric organ was cloned by expressing hybrid-depleted messenger RNA in Xenopus oocytes. The predicted protein has a sequence of 805 amino acids containing several putative membrane-spanning domains. Expression of the protein in Xenopus oocytes shows that it is sufficient for channel function. © 1990 Nature Publishing Group.

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页码：510 / 514

页数：5

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