D-GALACTOSE-DERIVED D-GALACTURONIC ACID-DERIVATIVES SUITABLE AS GLYCOSYL ACCEPTORS

被引：18

作者：

STEFFAN, W ^{[1
]}

VOGEL, C ^{[1
]}

KRISTEN, H ^{[1
]}

机构：

[1] UNIV ROSTOCK,SEKT CHEM,BUCHBINDERSTR 9,O-2500 ROSTOCK,GERMANY

来源：

CARBOHYDRATE RESEARCH | 1990年 / 204卷

关键词：

D O I：

10.1016/0008-6215(90)84026-Q

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Allyl (1a) and benzyl (1b) β-d-galactopyranosides were converted into methyl [allyl (and benzyl) 2-O-acetyl-3,4-O-isopropylidene-β-d-galactopyranosid]uronates, (6a and 6b) by three different routes. The carboxyl group was introduced by Jones oxidation of suitably protected precursors and esterified directly. The chemical behaviour of 6-O-trityl-, 6-O-(4,4′-dimethoxytrityl)-, and 6-O-(2-methoxypropane-2-yl)-derivatives was investigated. The overall yields obtained were strongly influenced by the protecting groups used, in particular their stability in acidic solution. © 1990.

引用

页码：109 / 120

页数：12

共 23 条

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