DIAGNOSIS OF HELICOBACTER-PYLORI INFECTION IN ADULT AND PEDIATRIC-PATIENTS BY USING PYLORISET, A RAPID LATEX AGGLUTINATION-TEST

被引:62
作者
WESTBLOM, TU
MADAN, E
GUDIPATI, S
MIDKIFF, BR
CZINN, SJ
机构
[1] MARSHALL UNIV,SCH MED,DEPT PATHOL,HUNTINGTON,WV 25702
[2] CASE WESTERN RESERVE UNIV,DEPT PEDIAT,CLEVELAND,OH 44106
关键词
D O I
10.1128/JCM.30.1.96-98.1992
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Pyloriset (Orion Diagnostica, Espoo, Finland) is a rapid antibody test using latex particles coated with acid-extracted antigen of Helicobacter pylori. We evaluated its ability to predict infection in 100 adult patients and 50 pediatric patients referred for gastric endoscopy. Sixty of 65 H. pylori-infected adults were correctly identified by the test. There were 12 false-positive and 5 false-negative reactions seen. Pyloriset had a sensitivity of 92% and a specificity of 66%. The positive predictive value was 83% and the negative predictive value 82%. In contrast, sensitivity dropped to 36% in the pediatric patients and the positive predictive value was only 40%. Pyloriset could become an important alternative to other more time-consuming diagnostic tests for H. pylori-infected adult patients but is inadequate for diagnosis of pediatric H. pylori infection.
引用
收藏
页码:96 / 98
页数:3
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