HEAT-SHOCK PROTEINS IN MULTIPLE-SCLEROSIS AND OTHER AUTOIMMUNE-DISEASES

被引：63

作者：

GEORGOPOULOS, C

MCFARLAND, H

机构：

[1] Costa Georgopoulos and Henry McFarland are, the Neuroimmunology Branch, National Institute of Neurological Disorders and Stroke, Bethesda

来源：

IMMUNOLOGY TODAY | 1993年 / 14卷 / 08期

关键词：

D O I：

10.1016/0167-5699(93)90135-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Because of the abundance of the highly conserved beat shock proteins (hsp) in microbial pathogens and in mammalian cells, hsps have been considered candidates as target antigens in autoimmune disorders such as multiple sclerosis (MS). Consequently, this workshop* examined the current understanding of the biology of hsps and discussed the evidence that they may contribute to autoimmune disease processes. This article reports the outcome of the discussion.

引用

页码：373 / 375

页数：3