BONE-MINERAL DENSITY DURING TREATMENT OF CENTRAL PRECOCIOUS PUBERTY

被引：40

作者：

NEELY, EK ^{[1
]}

BACHRACH, LK ^{[1
]}

HINTZ, RL ^{[1
]}

HABIBY, RL ^{[1
]}

SLEMENDA, CW ^{[1
]}

FEEZLE, L ^{[1
]}

PESCOVITZ, OH ^{[1
]}

机构：

[1] INDIANA UNIV, MED CTR, DEPT PEDIAT, INDIANAPOLIS, IN 46204 USA

来源：

JOURNAL OF PEDIATRICS | 1995年 / 127卷 / 05期

关键词：

D O I：

10.1016/S0022-3476(95)70182-6

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Treatment of adults with gonadotropin releasing hormone analogs has resulted in rapid loss in bone mineral density (BMD). We measured lumbar and femoral neck BMD by dual-energy x-ray absorptiometry during 2 years of depot leuprolide therapy in 13 girls (mean age, 7.5 years; mean bone age, 10.9 years). At baseline, BMD was elevated for age and concordant with the advanced skeletal age, During therapy with gonadotropin releasing hormone analog, BMD values increased and BMD standard deviation scores for age and skeletal age did not change.

引用

页码：819 / 822

页数：4

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