REPRESENTATIONAL DIFFERENCE ANALYSIS - FINDING THE DIFFERENCES BETWEEN GENOMES

被引：61

作者：

LISITSYN, NA

机构：

[1] Cold Spring Harbor Laboratory, Cold Spring Harbor, NY 11724

来源：

TRENDS IN GENETICS | 1995年 / 11卷 / 08期

关键词：

D O I：

10.1016/S0168-9525(00)89087-3

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Representational difference analysis (RDA) is an efficient method for finding the differences between complex genomes. The numerous applications of RDA include the cloning of probes for the detection of genetic lesions in cancer, the identification of sequences from the genomes of unknown pathogens and the rapid isolation of polymorphic markers linked to a trait without tbe use of pre-existing genetic maps.

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收藏

页码：303 / 307

页数：5

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[10]

LISITSYN NA, IN PRESS GENOME ANAL