INVITRO AND INVIVO ASSESSMENT OF HEPATIC AND EXTRAHEPATIC METABOLISM OF DIAZEPAM IN THE RAT

被引：30

作者：

IGARI, Y ^{[1
]}

SUGIYAMA, Y ^{[1
]}

SAWADA, Y ^{[1
]}

IGA, T ^{[1
]}

HANANO, M ^{[1
]}

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

来源：

JOURNAL OF PHARMACEUTICAL SCIENCES | 1984年 / 73卷 / 06期

关键词：

D O I：

10.1002/jps.2600730631

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：826 / 828

页数：3

共 34 条

[1]

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[2]

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[3] TRANSPORT AND BINDING OF METHOTREXATE IN-VIVO [J].

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ZAHARKO, DS ;

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[4] IN-VITRO-IN-VIVO CORRELATION OF DRUG-METABOLISM - DEAMINATION OF 1-BETA-D-ARABINOFURANOSYLCYTOSINE [J].

DEDRICK, RL ;

FORRESTER, DD ;

HO, DHW .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (01) :1-+

[5]

DESILVA JAF, 1966, FED PROC, V25, P532

[6] BLOOD LEVEL DISTRIBUTION PATTERNS OF DIAZEPAM AND ITS MAJOR METABOLITE IN MAN [J].

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KOECHLIN, BA ;

BADER, G .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1966, 55 (07) :692-&

[7]

DEVEREUX TR, 1979, DRUG METAB DISPOS, V7, P70

[8] FAILURE OF VARIOUS DRUGS TO INDUCE DRUG-METABOLIZING ENZYMES IN EXTRAHEPATIC TISSUES OF RAT [J].

FEUER, G ;

SOSALUCE.JC ;

LUMB, G ;

MODDEL, G .

TOXICOLOGY AND APPLIED PHARMACOLOGY, 1971, 19 (04) :579-&

[9]

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[10]

HAYES JS, 1976, BIOCHEM PHARMACOL, V25, P1495

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