ELECTROPHILE-INDUCED CYCLIZATION OF GAMMA,DELTA-ALKENYLIMINES AS A SYNTHETIC ROUTE TO PYRROLIDINES AND PIPERIDINES

被引：50

作者：

DEKIMPE, N

BOELENS, M

PIQUEUR, J

BAELE, J

机构：

[1] Department of Organic Chemistry, Faculty of Agricultural and Applied Biological Sciences, University of Gent, B-9000 Gent

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(00)73197-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Cyclization of gamma,delta-alkenylimines with bromine in dichloromethane gave instantaneous formation of cyclic iminium bromides, which were converted into either pyrrolidines or piperidines, depending upon the substitution pattern. This reaction has been applied in the synthesis of 2-azaspiro compounds.

引用

页码：1925 / 1928

页数：4

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