ABNORMALITY OF CEREBRAL GANGLIOSIDES IN FUKUYAMA TYPE CONGENITAL MUSCULAR-DYSTROPHY

被引：10

作者：

IZUMI, T

HARA, K

OGAWA, T

OSAWA, M

SAITO, K

NOVO, MDLP

FUKUYAMA, Y

TAKASHIMA, S

机构：

[1] TOKYO WOMENS MED COLL,DEPT PEDIAT,TOKYO,JAPAN

[2] NCNP,NATL INST NEUROSCI,TOKYO,JAPAN

来源：

BRAIN & DEVELOPMENT | 1995年 / 17卷 / 01期

关键词：

FCMD; GANGLIOSIDE; ABNORMAL DEVELOPMENTAL PATTERN; PERCENT DISTRIBUTION OF G(M1); G(D1A) AND G(M4);

D O I：

10.1016/0387-7604(94)00114-D

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Compared with DMD cases and non-neuromuscular disease controls, FCMD cases showed a reduction of total gangliosides, and an abnormal, immature ganglioside pattern in the cerebral gray and white matter. However, G(M4), which is only found in myelin and oligodendroglia, and is a unique quantitative marker of myelination, was present in a relatively high percentage in the white matter, which showed frontal lobe micropolygyria and diffuse low density on CT and MR T-1-imaging.

引用

页码：33 / 37

页数：5

共 20 条

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LIPID-COMPOSITION OF RAT CNS AXOLEMMA-ENRICHED FRACTIONS [J].