MECHANISM OF THE IRREVERSIBLE DEACTIVATION OF ARACHIDONATE 5-LIPOXYGENASE BY 5,6-DEHYDROARACHIDONATE

被引：25

作者：

COREY, EJ

LANSBURY, PT

CASHMAN, JR

KANTNER, SS

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1984年 / 106卷 / 05期

关键词：

D O I：

10.1021/ja00317a063

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

页码：1501 / 1503

页数：3

共 11 条

[1] IRREVERSIBLE INHIBITION OF THE LEUKOTRIENE PATHWAY BY 4,5-DEHYDROARACHIDONIC ACID [J].

COREY, EJ ;

KANTNER, SS ;

LANSBURY, PT .

TETRAHEDRON LETTERS, 1983, 24 (03) :265-268

[2]

COREY EJ, 1972, TETRAHEDRON LETT, P3769

[3] IRREVERSIBLE INHIBITION OF THE ENZYMIC OXIDATION OF ARACHIDONIC-ACID TO 15-(HYDROPEROXY)-5,8,11(Z),13(E)-EICOSATETRAENOIC ACID (15-HPETE) BY 14,15-DEHYDROARACHIDONIC ACID [J].

COREY, EJ ;

PARK, H .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (06) :1750-1752

[4] IRREVERSIBLE INHIBITION OF PROSTAGLANDIN AND LEUKOTRIENE BIOSYNTHESIS FROM ARACHIDONIC-ACID BY 11,12-DEHYDROARACHIDONIC AND 5,6-DEHYDROARACHIDONIC ACIDS, RESPECTIVELY [J].

COREY, EJ ;

MUNROE, JE .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1982, 104 (06) :1752-1754

[5] STEREOCHEMICAL COURSE OF 5-LIPOXYGENATION OF ARACHIDONATE BY RAT BASOPHIL LEUKEMIC-CELL (RBL-1) AND POTATO ENZYMES [J].

COREY, EJ ;

LANSBURY, PT .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1983, 105 (12) :4093-4094

[6] CHEMICAL STUDIES ON SLOW REACTING SUBSTANCES LEUKOTRIENES [J].

COREY, EJ .

EXPERIENTIA, 1982, 38 (11) :1259-1275

[7] SHORT, STEREOCONTROLLED SYNTHESES OF IRREVERSIBLE EICOSANOID BIOSYNTHESIS INHIBITORS - 5,6-DEHYDROARACHIDONIC,8,9-DEHYDROARACHIDONIC, AND 11,12-DEHYDROARACHIDONIC ACID [J].

COREY, EJ ;

KANG, J .

TETRAHEDRON LETTERS, 1982, 23 (16) :1651-1654

[8] DOCOSAHEXAENOIC ACID IS A STRONG INHIBITOR OF PROSTAGLANDIN BUT NOT LEUKOTRIENE BIOSYNTHESIS [J].

COREY, EJ ;

SHIH, C ;

CASHMAN, JR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1983, 80 (12) :3581-3584

[9] MEDIATION OF LOCAL HOMEOSTASIS AND INFLAMMATION BY LEUKOTRIENES AND OTHER MAST CELL-DEPENDENT COMPOUNDS [J].

LEWIS, RA ;

AUSTEN, KF .

NATURE, 1981, 293 (5828) :103-108

[10]

RAZIN E, J IMMUNOL

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