POLY(RA) BINDS POLY(RG).POLY(RC) TO FORM A TRIPLE HELIX

被引：20

作者：

CHASTAIN, M ^{[1
]}

TINOCO, I ^{[1
]}

机构：

[1] UNIV CALIF BERKELEY,CHEM BIODYNAM LAB,BERKELEY,CA 94720

来源：

NUCLEIC ACIDS RESEARCH | 1992年 / 20卷 / 02期

关键词：

D O I：

10.1093/nar/20.2.315

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Poly(rA) binds poly(rG).poly(rC) to form a triple helix. Evidence for this structure includes ultraviolet absorbance mixing curves and melting curves, and circular dichroism spectroscopy. The formation of the triple helix depends on the length of the poly(rC) strand. Triple helix forms when the average length is around 100 nucleotides but does not form when the average length is about 500 nucleotides.

引用

页码：315 / 318

页数：4

共 17 条

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