MOLECULAR DIAGNOSIS OF SEPSIS: NEW ASPECTS AND RECENT DEVELOPMENTS

被引：169

作者：

Liesenfeld, O. ^{[1
]}

Lehman, L. ^{[2
]}

Hunfeld, K. -P. ^{[3
]}

Kost, G. ^{[4
,5
]}

机构：

[1] Roche Mol Diagnost, Med & Sci Affairs, Pleasanton, CA 94566 USA

[2] Univ Bern, Inselspital, Dept Anaesthesiol & Pain Med, CH-3010 Bern, Switzerland

[3] Northwest Med Ctr, Inst Lab Med Microbiol & Infect Control, D-60488 Frankfurt, Germany

[4] Univ Calif Davis, Sch Med, Dept Pathol, Davis, CA 95616 USA

[5] Univ Calif Davis, Sch Med, Lab Med, Davis, CA 95616 USA

来源：

EUROPEAN JOURNAL OF MICROBIOLOGY AND IMMUNOLOGY | 2014年 / 4卷 / 01期

关键词：

sepsis; molecular diagnostics; PCR; mass spectrometry; SeptiFast; microarray; blood culture; biomarker;

D O I：

10.1556/EuJMI.4.2014.1.1

中图分类号：

Q93 [微生物学];

学科分类号：

071005 [微生物学]; 100705 [微生物与生化药学];

摘要：

By shortening the time to pathogen identification and allowing for detection of organisms missed by blood culture, new molecular methods may provide clinical benefits for the management of patients with sepsis. While a number of reviews on the diagnosis of sepsis have recently been published we here present up-to-date new developments including multiplex PCR, mass spectrometry and array techniques. We focus on those techniques that are commercially available and for which clinical studies have been performed and published.

引用

页码：1 / 25

页数：25

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