BIOMASS ESTIMATION USING ONLINE GLUCOSE MONITORING BY FLOW-INJECTION ANALYSIS - APPLICATION TO CANDIDA-RUGOSA BATCH GROWTH

被引：11

作者：

VALERO, F ^{[1
]}

LAFUENTE, J ^{[1
]}

POCH, M ^{[1
]}

SOLA, C ^{[1
]}

机构：

[1] UNIV AUTONOMA BARCELONA,UNITAT ENGN QUIM,BARCELONA,SPAIN

来源：

APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY | 1990年 / 24-5卷

关键词：

D O I：

10.1007/BF02920281

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A new Flow Injection Analysis (FIA) system was developed that permits the on-line monitoring of glucose. This information may be used to identify the biomass concentration. The proposed manifold allows the automatic analysis of glucose from 0 to 90 g/L. The results are in agreement with the analyses provided by HPLC. The system was applied to on-line monitoring of substrate in several Candida rugosa batches grow without detecting mechanical or biochemical problems. This information was linked to a Extended Kaiman Filter (EKF) recursive estimation scheme to identify the vector state of the system. Index Entries: Flow Injection Analysis; on-line glucose analysis; biomass identification; Candida rugosa. © 1990 Humana Press Inc.

引用

页码：591 / 602

页数：12

共 16 条

[1]

ADKISSON B, 1983, BIOCH ENG BIOTECHNOL

[2]

BELLGARDT KH, 1984, 3RD P EUR C BIOTECHN, V2, P607

[3] APPLICATION OF EXTENDED KALMAN FILTER TO IDENTIFICATION OF ENZYMATIC DEACTIVATION [J].

CAMINAL, G ;

LAFUENTE, J ;

LOPEZSANTIN, J ;

POCH, M ;

SOLA, C .

BIOTECHNOLOGY AND BIOENGINEERING, 1987, 29 (03) :366-369

[4]

CHERUY A, 1988, RESULTATS PERSPECTIV

[5] ADAPTIVE IDENTIFICATION AND CONTROL ALGORITHMS FOR NONLINEAR BACTERIAL-GROWTH SYSTEMS [J].

DOCHAIN, D ;

BASTIN, G .

AUTOMATICA, 1984, 20 (05) :621-634

[6] CONTINUOUS, RELIABLE ONLINE ANALYSIS OF FERMENTATION MEDIA BY SIMPLE ENZYMATIC SPECTROPHOTOMETRIC ASSAYS [J].

GIBSON, TD ;

WOODWARD, JR .

ANALYTICA CHIMICA ACTA, 1988, 213 (1-2) :61-68

[7]

Himmelblau DM., 2018, APPL NONLINEAR PROGR

[8]

Kalman R. E., 1961, J BASIC ENG-T ASME, V83, P95, DOI DOI 10.1115/1.3658902

[9] ONLINE PARAMETER AND STATE ESTIMATION OF CONTINUOUS CULTIVATION BY EXTENDED KALMAN FILTER [J].

NAHLIK, J ;

BURIANEC, Z .

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, 1988, 28 (02) :128-134

[10] STEROL REQUIREMENT FOR LIPASE PRODUCTION BY CANDIDA CYLINDRACEA [J].

OTA, Y ;

MIYAIRI, S ;

YAMADA, K .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1968, 32 (12) :1476-&

← 1 2 →