IMMUNIZATION AGAINST EXPERIMENTAL COCCIDIOSIS PRODUCES CONTRASTING RESULTS IN INBRED MICE OF DIFFERING SUSCEPTIBILITY TO INFECTION

被引：10

作者：

ROSE, ME ^{[1
]}

HESKETH, P ^{[1
]}

WAKELIN, D ^{[1
]}

机构：

[1] UNIV NOTTINGHAM,DEPT LIFE SCI,NOTTINGHAM NG7 2RD,ENGLAND

来源：

INFECTION AND IMMUNITY | 1994年 / 62卷 / 02期

基金：

英国惠康基金;

关键词：

D O I：

10.1128/IAI.62.2.733-737.1994

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pretreatment of inbred mice with intravenous and/or intraperitoneal injection of an antigen prepared from sporozoites of Eimeria ia vermiformis modulated the course of infection with the parasite in a manner that depended on the resistance-susceptibility phenotype of the host. Mice with a resistant background (BALB) produced more oocysts and those with a susceptible background (C57BL) produced fewer oocysts than their respective controls. The optimum conditions for producing these effects were established, and evidence is presented which suggests that the phenomenon might also apply in the target host, the chicken.

引用

页码：733 / 737

页数：5

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