FUNCTIONALIZED CHLOROENAMINES IN AMINOCYCLOPROPANE SYNTHESIS .12. BASICITY AND PROTONATION BEHAVIOR OF 6-AMINO-3-AZABICYCLO[3.1.0]HEXANE DERIVATIVES

被引：11

作者：

BUTZ, V ^{[1
]}

VILSMAIER, E ^{[1
]}

MAAS, G ^{[1
]}

机构：

[1] UNIV KAISERSLAUTERN,FACHBEREICH CHEM,ERWIN SCHRODINGER STR,D-67663 KAISERSLAUTERN,GERMANY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2 | 1993年 / 10期

关键词：

D O I：

10.1039/p29930001907

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Bicyclic endo diamines 1a-c are more basic than the diastereomeric exo diamines 2a-c by about one pK(a) unit. Configuration and conformation of some compounds 5, the monoammonium salts of the endo diamines 1, have been studied by H-1 NMR spectroscopy. X-Ray structure analysis of salt 5n Br, possessing the N(3)-H proton in the endo position, indicates a hydrogen bonding with the bromide anion rather than with the C(6)-morpholine unit.

引用

页码：1907 / 1913

页数：7

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