GENOMIC SEQUENCE AND ORGANIZATION OF 2 MEMBERS OF A HUMAN LECTIN GENE FAMILY

被引：85

作者：

GITT, MA ^{[1
]}

BARONDES, SH ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,LANGLEY PORTER NEUROPSYCHIAT INST,DEPT PSYCHIAT,401 PARNASSUS AVE,SAN FRANCISCO,CA 94143

来源：

BIOCHEMISTRY | 1991年 / 30卷 / 01期

关键词：

D O I：

10.1021/bi00215a013

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

We have isolated and sequenced the genomic DNA encoding a human dimeric soluble lactose-binding lectin. The gene has four exons, and its upstream region contains sequences that suggest control by glucocorticoids, heat (environmental) shock, metals and other factors. We have also isolated and sequenced three exons of the gene encoding another human putative lectin, the existence of which was first indicated by isolation of its cDNA. Comparisons suggest a general pattern of genomic organization of members of this lectin gene family.

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页码：82 / 89

页数：8

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