FAST SOLUTE RELEASE FROM PHOTOSENSITIVE LIPOSOMES - AN ALTERNATIVE TO CAGED REAGENTS FOR USE IN BIOLOGICAL-SYSTEMS

被引：30

作者：

MORGAN, CG ^{[1
]}

BISBY, RH ^{[1
]}

JOHNSON, SA ^{[1
]}

MITCHELL, AC ^{[1
]}

机构：

[1] UNIV SALFORD, DEPT BIOL SCI, SALFORD M5 4WT, LANCS, ENGLAND

来源：

FEBS LETTERS | 1995年 / 375卷 / 1-2期

基金：

英国工程与自然科学研究理事会;

关键词：

LIPOSOME; PHOTOCHROMISM; PHOTOLYSIS; LASER; SOLUTE RELEASE;

D O I：

10.1016/0014-5793(95)01193-I

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The kinetics of release of soluble marker trapped in liposomes of gel phase phospholipid containing a photoisomerisable phospholipid analogue have been investigated, Marker release is triggered by UV laser flash photolysis at 355 nm, A markedly temperature-dependent release rate is seen, and above 25 degrees C millisecond release kinetics can be achieved, These results suggest that such liposomes might find application as an alternative to conventional 'caged' reagents for photo-triggered reagent release in biological research.

引用

页码：113 / 116

页数：4

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