EVALUATION OF A METHOD FOR SIMULTANEOUS QUANTIFICATION OF CODEINE, ETHYLMORPHINE AND MORPHINE IN BLOOD

被引：32

作者：

GJERDE, H

FONGEN, U

GUNDERSEN, H

CHRISTOPHERSEN, AS

机构：

[1] National Institute of Forensic Toxicology, N-0320 Oslo

来源：

FORENSIC SCIENCE INTERNATIONAL | 1991年 / 51卷 / 01期

关键词：

CODEINE; ETHYLMORPHINE; MORPHINE; BLOOD; METHOD;

D O I：

10.1016/0379-0738(91)90210-A

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Codeine, ethylmorphine and morphine are the most commonly detected opiates in forensic blood samples in Norway. A method for the simultaneous quantification of these opiates utilizing solid phase extraction and gas chromatography-mass spectrometry has been evaluated. The detection limits were 0.026-mu-mol/l for codeine, 0.025-mu-mol/l for ethylmorphine and 0.032-mu-mol/l for morphine (corresponding to 7.8, 7.8 and 9.1-mu-g/l, respectively). The analytical variations at concentrations of 1.0-mu-mol/l codeine, 1.0-mu-mol/l ethylmorphine and 0.5-mu-mol/l morphine were less than 5%.

引用

页码：105 / 110

页数：6